Targeted inhibition of Aurora kinase A promotes immune checkpoint inhibition efficacy in human papillomavirus-driven cancersSoma Ghosh, Madison P O'Hara, Pragya Sinha, Tuhina Mazumdar, Lacin Yapindi, Jagannadha K Sastry, Faye M Johnson
7 January 2025
Durvalumab and tremelimumab in combination with metronomic oral vinorelbine for recurrent advanced cervical cancer: an open-label phase I/II studyJean-Sébastien Frenel, Laurent Mathiot, Claire Cropet, Edith Borcoman, Alice Hervieu, Elodie Coquan, Thibault De La Motte Rouge, Esma Saada-Bouzid, Renaud Sabatier, Pernelle Lavaud, Marta Jimenez, François Legrand, Olivia Le Saux, Emmanuelle Charafe, Anthony Gonçalves
7 January 2025
Divergent response to radio-immunotherapy is defined by intrinsic features of the tumor microenvironmentJacob Gadwa, Justin Yu, Miles Piper, Michael W Knitz, Laurel B Darragh, Nicholas Olimpo, Sophia Corbo, Jessica I Beynor, Brooke Neupert, Alexander T Nguyen, Chloe Hodgson, Diemmy Nguyen, Khalid NM Abdelazeem, Anthony Saviola, Laurene PousseSee the full list of authors
7 January 2025
Safety and efficacy of the therapeutic DNA-based vaccine VB10.16 in combination with atezolizumab in persistent, recurrent or metastatic HPV16-positive cervical cancer: a multicenter, single-arm phase 2a studyPeter Hillemanns, Michal Zikan, Frédéric Forget, Hannelore G Denys, Jean-Francois Baurain, Lukas Rob, Linn Woelber, Pawel Blecharz, Mariusz Bidzinski, Josef Chovanec, Frederik Marmé, Theresa Link, Christian Dannecker, Anders Rosholm, Kaja C G BergSee the full list of authors
7 January 2025
Depletion of myeloid-derived suppressor cells sensitizes murine multiple myeloma to PD-1 checkpoint inhibitorsWei Xiong, Liuling Xiao, Rui Duan, Qiang Wang, Miao Xian, Chuanchao Zhang, Pan Su, Yabo LI, Ling Zhong, Jianfei Qian, Chengyun Zheng, Qing Yi
4 January 2025
Early treatment discontinuation in patients with deficient mismatch repair or microsatellite instability high metastatic colorectal cancer receiving immune checkpoint inhibitorsJulien Taieb, Margherita Ambrosini, Emily Alouani, Sara Lonardi, Frank A Sinicrope, Marie Decraecker, Alice Boileve, Emilie Hafliger, Thibault Mazard, Simon Pernot, Pauline Parent, Javier Ros, Michael J Overman, Priya Jayachandran, Vincenzo NascaSee the full list of authors
4 January 2025
Neoadjuvant atezolizumab + chemotherapy for resectable NSCLC: 3-year clinical update of phase II clinical trial results and translational findingsBrian S Henick, Peter D Koch, Justin F Gainor, Mark M Awad, Codruta Chiuzan, Stephanie Izard, Yohanna Georgis, Samyukta Mallick, Robert F Garofano, Cheryl V Wong, Anjali Saqi, Jessica Grindheim, Katja Schulze, Joshua R Sonett, Naiyer A RizviSee the full list of authors
25 December 2024
Krebs von den Lungen-6 surveillance in immune checkpoint inhibitor-induced pneumonitisRyosuke Matsukane, Shoji Nakamura, Haruna Minami, Kazuya Tsubouchi, Yasuto Yoneshima, Kojiro Hata, Sai Yasukochi, Kimitaka Suetsugu, Isamu Okamoto, Takeshi Hirota
22 December 2024
Optimal timing of anti-PD-1 antibody combined with chemotherapy administration in patients with NSCLCYachang Huo, Dan Wang, Shuangning Yang, Yujie Xu, Guohui Qin, Chenhui Zhao, Qingyang Lei, Qitai Zhao, Yaqing Liu, Kaiyuan Guo, Songyun Ouyang, Ting Sun, Hongmin Wang, Feifei Fan, Na HanSee the full list of authors
19 December 2024
Blocking IL1RAP on cancer-associated fibroblasts in pancreatic ductal adenocarcinoma suppresses IL-1-induced neutrophil recruitmentNils Hansen, Pablo Peña-Martínez, Petter Skoog, Katrin Reinbach, Finja C Hansen, Susanne Larsson Faria, Caitríona Grönberg, Kawther Abdilleh, Susanne Magnusson, Karin von Wachenfeldt, Camilla Rydberg Millrud, David Liberg, Marcus Järås
18 December 2024